Summary of the Genetic Disorder and Symptoms |
According to the FH Foundation, Familial Hypercholesterolemia (FH) is a mutation from the LDLR gene in the body (“What is Familial Hypercholesterolemia?”). This gene is passed along from parents and there is a 50% chance you will pass it along to your children. This mutation causes you to have high cholesterol, high cholesterol causes heart attacks increased by 50% for men and 30% from women by 50 years of age. According to the FH (Familial Hypercholesterolemia) foundation FH can cause diseases or something like heart attack problems and strokes.
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Treatments
According to The FH Foundation, a low fat diet wont make anything better but it will help make the symptoms less apparent (via “Hypercholesterolemia Treatment.” The FH Foundation). Some of the medication you can use is, Cholesterol absorber which goes into the intestine to lower Cholesterol, absorption in the bloodstream or BIle acid sequestrant, which does around the same thing as Cholesterol absorption but not in the bloodstream. There are other treatments, but those are the main ones.
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Mode of Genetic Inheritance
According to the U.S National Library of Medicine , FH is caused by a defect in chromosome 19. (Genetics Home Reference) This causes the body to not be able to move low density food. If a parent with FH decides to have kids their children have a 50% chance of inheriting FH. The child could also be born with high Cholesterol.
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How common is the Genetic Disorder
According to the “FH Foundation” FH is common but Homozygous Familial Hypercholesterolemia is not common and only affects 1 in 160,000 people world wide( FH Foundation). FH affects 1 in 500 people worldwide, but occurred more frequently in certain countries like, South Africa, French Canadians, Lebanese and Finns.
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3 Current Research Project
According to FH Foundation Over 90% of the 1.3 million people in the U.S that have FH, don't get treated for it (“Familial Hypercholesterolemia”).
Also according to the Mayo Clinic their can be a high risk when taking new drugs and other kinds of treatments. According to Mayo Clinic, high cholesterol can sometimes be unhealthy for a lifestyle choice and it prevents an untreatable. |